Established in 1990 by Mrs. Ansari and Mrs. Jackson, the School of Knowledge provides high-quality education for students from Kindergarten to Grade 6. The school was initially started in a villa in Ghafia, with only 45 students and 10 teachers Under the commendable leadership of Mrs. Ansari and Mrs. Jackson the strength grew in leaps and bounds, and in 2005, it was shifted to its present location in the Al Azra area. Today it has over 110 teachers and 1800 students and established its name delivering on all counts be it academics or co-curricular activities. The three core goals of the school are Academic Excellence, Character Building, and Leadership- Training.

In the year 2012, the School of Knowledge was taken over by His Excellency Bishop Paul Hinder and was added to the St. Mary's group of schools, which has its presence in Dubai, Abu Dhabi, and Fujairah too. The management has plans of expansion to provide education to students to the A level.